Cytokines

Human HBEGF

Product Code: GFC0060

Description

Heparin-binding EGF like growth factor (HBEGF) is a member of the EGF family. HBEGF promotes blastocyst adhesion to the uterine wall. It also plays a role in smooth muscle cell hyperplasia and brain injury. HBEGF produced by CD4+ T cells promotes wound healing by stimulating migration and proliferation of keratinocytes, fibroblasts, and smooth muscle cells.

Specification

Source

E. coli

Symbols

Diphtheria toxin receptor, DTR, HBEGF, Heparin binding EGF-like growth factor, DTS, DTSF, HEGFL

Accession

Q99075

AA Sequence

DLQEADLDLLRVTLSSKPQALATPNKEEHGKRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSL

Molecular Mass

9.7 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using 3T3 cells is ≥ 1.3 x 10^6 units/mg (EC50 ≤ 0.75 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.