Cytokines

Human FGF9

Product Code: GFC0051

Description

Fibroblast growth factor 9 (FGF9) is a member of the fibroblast growth factor (FGF) family. FGF9 signals by binding FGFR3 (IIIb) and the IIIc splice variants of the FGFR1, FGFR2, and FGFR3 receptors. FGF9 was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development.

Specification

Source

E. coli

Symbols

Fibroblast growth factor-9, GAF, Glia-activating factor, HBGF-9

Accession

P31371

AA Sequence

MAPLGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS

Molecular Mass

23.4 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using 3T3 cells is ≥ 5 x 10^5 units/mg (EC50 ≤ 2 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.