Cytokines

Human FGF8, animal component-free

Product Code: GFC0050

Description

Fibroblast growth factor 8 (FGF8) is a member of the fibroblast growth factor (FGF) family. The FGF family possesses broad mitogenic and cell survival activities and is involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis. FGF8 is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells.

Specification

Source

E. coli

Symbols

AIGF, Androgen-induced growth factor, FGF-8, Fibroblast growth factor-8B, HBGF-8, Heparin-binding growth factor-8, HH6, KAL6

Accession

P55075

AA Sequence

MQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR

Molecular Mass

22.5 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using NR6R 3T3 cells is ≥ 6.7 x 10^3 units/mg (EC50 ≤ 150 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.