Cytokines

Human FGF5

Product Code: GFC0045

Description

Fibroblast growth factor 5 (FGF5) is a member of the fibroblast growth factor (FGF) family. FGF5 promotes cell differentiation and proliferation by binding FGF receptor 1 and FGF receptor 2 (FGFR1 and FGFR2, respectively). It plays an important regulatory role in skeletal muscle development. FGF5 has also been identified in neurons of the limbic system, especially those of the olfactory bulb and pyramidal cells of the hippocampus.

Specification

Source

E. coli

Symbols

Fibroblast growth factor 5, HBGF-5, Heparin-binding growth factor 5, Smag-82

Accession

P12034

AA Sequence

MAWAHGEKRLAPKGQPGPAATDRNPIGSSSRQSSSSAMSSSSASSSPAASLGSQGSGLEQSSFQWSPSGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFLPRFKQSEQPELSFTVTVPEKKNPPSPIKSKIPLSAPRKNTNSVKYRLKFRFG

Molecular Mass

27.7 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by a cell proliferation assay using NR6R-3T3 cells in the presence of 1 μg heparin is ≥ 1.0 x 10^5 units/mg (EC50 ≤ 10 ng/mL).

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.