Cytokines

Mouse CXCL12

Product Code: GFC0032

Description

CXCL12 is a member of the alpha chemokine protein family. It is secreted protein and functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4. CXCL12 plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis.

Specification

Source

CHO

Symbols

CXCL12, PBSF, SDF-1 α, Stromal cell-derived factor-1

Accession

Q4FJL5

AA Sequence

KPVSLSYRCPCRFFESHIARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK

Molecular Mass

8 kDa

Purity

≥ 95%

Bioactivity

The specific activity as determined by Ca2+ mobilization assay using CHO-K1 cells stably expressing human Gα15 and mouse CXCR4 is ≥ 6.7 x 10^2 units/mg (EC50 ≤ 1.5 μg/mL) .

Storage

Store at -80°C. Avoid repeated freeze-thaw cycles.

For research or further manufacturing use only. Not for use in humans.