Product Code: CB0586
Catalog Number | Unit Size | Price |
---|---|---|
CB0586-10 mg | 10 mg | Online Inquiry |
Description
Procaspase-activating compound 1 directly activates procaspase-3 to caspase-3, a transformation that allows induction of apoptosis even in cells that have defective apoptotic machinery. In cancer cells, PAC-1 had an IC₅₀ value of 3 nM for induction of cell death, whereas in cells from adjacent normal tissue had IC₅₀ values of 3.2-8.5 µM.
Specification