Trichostatin A

Product Code: CB0547

Catalog Number Unit Size Price
CB0547-1 mg 1 mg Online Inquiry

Description

Potent histone deacetylase inhibitor. Trichostatin A induces accelerated dedifferentiation of primordial germ cells (PGCs) into embryonic germ (EG) cells. In an animal model of Huntington's disease, inhibition of HDAC by Trichostatin A rescues memory deficits and increases expression of CREB/CBP target genes in mutant mice.

Specification

Chemical Name
(2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Formula
C17H22N2O3
Molecular Weight
302.37
Purity
≥97% (HPLC)
CAS No.
58880-19-6
PubChem
444732
InChi Key
RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES String
O=C([C@H](C)/C=C(C)/C=C/C(NO)=O)C1=CC=C(N(C)C)C=C1
Storage
Store at -20°C. Store under desiccating conditions.
For research or further manufacturing use only. Not for use in humans.

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