DBZ

Product Code: CB0435

Catalog Number	Unit Size	Price
CB0435-10 mg	10 mg	Online Inquiry
CB0435-50 mg	50 mg	Online Inquiry

Description

γ-secretase inhibitor. By inhibiting the Notch pathway, DBZ improves the efficiency of iPSC generation and production from mouse and human keratinocytes without KLF4 and CMYC. DBZ in combination with iDOT1L enables maintenance of human naïve-state pluripotency in non-hypoxic conditions.

Specification

Alternative Name

Dibenzazepine, YO-01027

Chemical Name

N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide

Formula

C26H23F2N3O3

Molecular Weight

463.48

Purity

≥98% (HPLC)

CAS No.

209984-56-5

PubChem

11454028

InChi Key

QSHGISMANBKLQL-OWJWWREXSA-N

SMILES String

CN1C2=C(C=CC=C2)C3=C(C=CC=C3)[C@H](NC([C@@H](NC(CC4=CC(F)=CC(F)=C4)=O)C)=O)C1=O

Storage

Store at -20°C. Store under desiccating conditions.

For research or further manufacturing use only. Not for use in humans.